Leukocytoclastic vasculitis following immunization with COVID-19 vaccine

Case report Introduction: Vaccines have been recognized as agents associated with development of different forms of vasculitis. We describe the case of a leukocytoclastic vasculitis which developed after immunization with inactivated COVID-19 vaccine. Case presentation: A 68-years old female patient presented with painful purpuric papules and plaques, and areas of necrosis, dominantly localized on her feet (Figure 1), developing 12 days after she received first dose of inactivated COVID-19 vaccine (BBIBP Cor-V). There were no other symptoms except mild fatigue and low-grade temperature of 37.3degreeC. Skin biopsy showed damaged vessel wall with perivascular, neutrophilic inflammatory infiltrate, leucocytoclasia and erythrocytes extravasation (Figure 2). Thorough work-up, including broad immunoserological and virological analysis didn't reveal any other potential trigger. Three months before vaccination the patient recovered from COVID-19 pneumonia. After the four weeks course of prednisone (initially 20 mg/day) with tapering a complete resolution of skin changes was achieved. The patient was followed for one year with no relapses. Conclusion(s): COVID-19 immunization should be considered as a potential trigger for development of cutaneous vasculitis.

Automatic device for remote measuring of circularity: Development and implementation in education courses

In conjunction with the development of technology, teaching in educational institutions around the world has also changed from traditional teaching, where blackboards and chalk were used, to modern teaching with blended or completely online learning environments. Online teaching became a necessity over the past year as the COVID-19 pandemic occurred throughout the world. One of the biggest problems that arose was the impossibility of students to work with equipment on the spot during laboratory exercises. In turn, many universities have used labs with physical devices that can be launched remotely through the Internet from anywhere. One such device is presented in this paper. An automatic device for the remote measurement of geometric tolerances, circularity, was developed and applied in the teaching process at the University of Novi Sad. The exercises were performed by students who remotely started and controlled the device and measured the deviation of the actual from the defined diameter of the work piece in the desired cross section. At the end of the semester, students completed an evaluation questionnaire and expressed satisfaction with the implementation of this exercise. © 2021 University of Kuwait. All rights reserved.